Mixing Alcohol And Antibiotics

Despite the fact that there are warnings not to consume alcohol on the majority of antibiotic packaging, it is a common misconception that drinking while on these medications is a relatively safe practice. In fact, one of the most frequently asked questions that doctors get regarding prescription antibiotics is, “is it safe to drink on these?” The short answer is no – alcohol directly inhibits the effectiveness of antibiotics and can additionally cause a wide range of negative side effects.

When the body breaks down alcohol, it produces acetaldehyde, which can cause nausea. Many people taking antibiotics already experience stomach or digestive side effects, and drinking alcohol while on these medications can increase feelings of nausea. In addition to gastrointestinal issues, both alcohol and antibiotics can hinder cognitive function, concentration, and coordination. Another thing to consider with alcohol and antibiotics is the fact that drinking interferes with the essential processes of the body like sleep and hydration, and these are critical components of recovering from a bacterial illness. Due to these factors, it’s best to stay away from alcohol for the duration of antibiotic treatment.

What Are Antibiotics?

Antibiotics, also known as antibacterial agents, are powerful medications that destroy or slow down the growth of bacteria. Antibiotics do not fight against infections caused by viruses such as colds or the flu, but instead bacterial diseases. Antibiotics work by either killing invading bacteria or stopping the antibodies from reproducing. While white blood cells in the body will usually attack harmful bacteria and cure the infection by itself, sometimes the number of foreign bacteria is too excessive, requiring antibiotics to help aid in the process.

There are several types of antibiotics available that treat a wide range of conditions, including:

Most antibiotics are relatively safe when used as directed; however, many antibiotics also come with a risk of side effects such as upset stomach, nausea, and diarrhea. All of these effects can be amplified when taken with alcohol and cause additional side effects like vomiting, dizziness, drowsiness, headache, and even potentially life-threatening seizures.

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The Effects Of Mixing Alcohol and Antibiotics

Below is a table that depicts the effects of drinking alcohol while on some of the most commonly prescribed antibiotics.

Antibiotic Class Antibiotic Should I Avoid Alcohol During Treatment? Effects of Mixing Alcohol and the Antibiotic
Tetracyclines Doxycycline Yes Reduced effect of antibiotic


Tetracyclines Minocycline Yes Liver Disease



Oxazolidinones Linezolid Yes Agitation

Unusual sweating


Altered mental status


Elevated blood pressure



Cardiac arrest

Muscle spasms

Sulfonamides Sulfamethoxazole

and Trimethoprim

Yes Folic acid deficiency



Fluoroquinolones Ciprofloxacin



Limit alcohol consumption Disturbances in attention


Memory loss


Nitroimidazole Metronidazole Yes Abdominal cramping




Facial flushing

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The Dangers Of Mixing Alcohol And Antibiotics

Both alcohol and antibiotics have individual sets of side effects that impact an individual’s behavior and mental state. Because of this, the two should never be mixed together. A handful of antibiotics can cause violent physical reactions when combined with alcohol. These include Metronidazole and Linezolid, which are commonly prescribed to treat intestinal tract and skin infections, and the sulfonamide medications of Sulfamethoxazole and Trimethoprim, which are used to treat everything from urinary tract infections to pneumonia to ear infections.

Consuming alcohol while taking these drugs can result in severe fatigue, a throbbing headache, dizziness, anxiety, chest pain, and heart palpitations. Alcohol can also worsen digestive side effects and turn into blood or mucus in stool, severe diarrhea, intense stomach cramping or pain, fever, uncontrollable vomiting. Mixing alcohol with certain antibiotics can also damage vital organs, including the liver. The kidneys are responsible for removing toxins, including medications, from the blood and body through urine. Antibiotics can overburden and damage kidneys and alcohol exacerbates this.

In addition to all of the debilitating side effects detailed above, alcohol can also hinder certain immune system processes and have a negative impact on the body’s ability to recover from an infection. Alcohol then not only slows the healing process and recovery time, but additionally puts an individual at increased risk of developing another infection.

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Avoid Alcohol While Taking Antibiotics

Drinking alcohol while taking antibiotics can be risky. Not only can alcohol interact badly with some medications and cause severe side effects, it can also potentially interrupt the natural healing process. Alcohol should be avoided until the regimen of antibiotics is completed and your body receives adequate rest and nutrition. However, if you’re someone that suffers from alcoholism, this may be easier said than done. If you think that you may be addicted to alcohol, contact a treatment provider to get started on the road to recovery today.

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If you or a loved one is ready to overcome an alcohol addiction, reach out today. Treatment providers can connect you with programs that provide the tools to help you get and stay sober.